Vitamin C levels in patients with
SARS-CoV-2-associated acute
respiratory distress syndrome
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Luis Chiscano-Camón,
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Juan Carlos Ruiz-Rodriguez,
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Adolf Ruiz-Sanmartin,
-
Oriol Roca &
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Ricard Ferrer
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ABSTRACT
Vitamin C is an antioxidant with anti-inflammatory
and immune-supportive properties. Its levels are
decreased in patients with sepsis-related acute
respiratory distress syndrome (ARDS). Moreover,
a significant number of patients with severe acute
respiratory syndrome coronavirus-2 (SARS-CoV-2)
disease developed ARDS [1]. Therefore, we
hypothesized that ARDS coronavirus disease 2019
(COVID-19) patients may present vitamin C deficiency.
LIMITATIONS
Our study has several limitations mainly related with
the fact that it is a unicentric study with small sample
size and blood sample was obtained in different days
of their course in the ICU.
CONCLUSION
In conclusion, in our cohort of patients with COVID-19-
associated ARDS, the levels of vitamin C are extremely
low. Despite the limited generalization of these results,
we think these findings might stimulate clinicians to measure
vitamin C levels in COVID-19 patients to describe the
real impact of this alteration.
